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Original Articles

  1. Bundo M, Toyoshima M, Okada Y, Akamatsu W, Ueda J, Nemoto-Miyauchi T, Sunaga F, Toritsuka M, Ikawa D, Kakita A, Kato M, Kasai K, Kishimoto T, Nawa H, Okano H, Yoshikawa T, Kato T*, Iwamoto K*. Increased L1 retrotransposition in the neuronal genome in schizophrenia. Neuron in press
  2. Mehta D, Iwamoto K, Ueda J, Bundo M, Adati N, Kojima T, Kato T*. Comprehensive survey of CNVs influencing gene expression in the human brain and its implications for pathophysiology. Neuroscience Research in press
  3. Iwata A*, Nagata K, Hatsuta H, Takuma H, Bundo M, Iwamoto K, Tamaoka K, Murayama S, Saido T, Tsuji S. Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation. Human Molecular Genetics in press
  4. Ikegame T, Bundo M, Sunaga F, Asai T, Nishimura F, Yoshikawa A, Kawamura Y, Hibino H, Tochigi M, Kakiuchi C, Sasaki T, Kato T, Kasai K, Iwamoto K*. DNA methylation analysis of BDNF gene promoters in peripheral blood cells of schizophrenia patients. Neuroscience Research in press
  5. Asai T, Bundo M, Sugawara H, Sunaga F, Ueda J, Tanaka G, Ishigooka J, Kasai K, Kato T, Iwamoto K*. Effect of mood stabilizers on DNA methylation in human neuroblastoma cells. International Journal of Neuropsychopharmacology in press
  6. Nishioka M, Shimada T, Bundo M, Ukai W, Hashimoto E, Saito T, Kano Y, Sasaki T, Kasai K, Kato T*, Iwamoto K*. Neuronal cell-type specific DNA methylation patterns of the Cacna1c gene. International Journal of Developmental Neuroscience 2013,31:89-95.
  7. Nishioka M, Bundo M, Koike S, Takizawa R, Kakiuchi C, Araki T, Kasai K, Iwamoto K*. Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia. Journal of Human Genetics 2013,58:91-97.
  8. Bundo M, Sunaga F, Ueda J, Kasai K, Kato T, Iwamoto K*. A systematic evaluation of whole genome amplification of bisulfite-modified DNA. Clinical Epigenetics 2012,4:22.
  9. Yu CC, Furukawa M, Kobayashi K, Shikishima C, Cha PC, Sese J, Sugawara H, Iwamoto K, Kato T, Ando J, Toda T*. Genome-wide DNA methylation and gene expression analyses of monozygotic twins discordant for intelligence levels. PLoS One 2012,7:e47081.
  10. Kato T*, Hayashi-Takagi A, Toyota T, Yoshikawa T, Iwamoto K*. Gene expression analysis in lymphoblastoid cells as a potential biomarker of bipolar disorder. Journal of Human Genetics 2011,11:779-783.
  11. Sugawara H, Iwamoto K, Bundo M, Ueda J, Miyauchi T, Komori A, Kazuno A, Adati N, Kusumi I, Okazaki Y, Ishigooka J, Kojima T, Kato T*. Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins. Translational Psychiatry 2011,1:e24.
  12. Yamada K, Iwayama Y, Hattori E, Iwamoto K, Toyota T, Ohnishi T, Ohba H, Maekawa M, Kato T, Yoshikawa T*. Genome-wide association study of schizophrenia in Japanese population. PLoS One 2011,6:e20468
  13. Iwamoto K*, Bundo M, Ueda J, Oldham MC, Ukai W, Hashimoto E, Saito T, Gescwind DH, Kato T*. Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons. Genome Research 2011,21:688-696.
  14. Iwamoto K*, Ueda J, Bundo M, Kojima T, Kato T*. Survey of the effect of genetic variations on gene expression in human prefrontal cortex and its application to genetics of psychiatric disorders. Neuroscience Research 2011,70:238-242.
  15. Sugawara H, Iwamoto K, Bundo M, Ueda J, Ishigooka J, Kato T*. Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines. Epigenetics 2011,6:508-515.
  16. Kubota M, Kasahara T, Iwamoto K, Komori A, Miyauchi T, Ishiwata M, Kato T*. Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder. International Journal of Neuropsychopharmacology 2010,13:1355-1368.

Reviews

  1. Kato T*, Iwamoto K. Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders. Neuropharmacology in press
  2. Hayashi-Takagi A*, Vawter MP, Iwamoto K. Peripheral biomarkers revisited: integrative profiling of peripheral samples for psychiatric research. Biological Psychiatry in press
  3. Ikegame T, Bundo M, Murata Y, Kasai K, Kato T, Iwamoto K*. DNA methylation of the BDNF gene and its relevance to psychiatric disorders. Journal of Human Genetics 2013,58:434-438.
  4. Sugawara H, Bundo M, Ishigooka J, Iwamoto K, Kato T*. Epigenetic regulation of serotonin transporter in psychiatric disorders. Journal of Genetics and Genomics 2013,40:325-329
  5. Nishioka M, Bundo M, Kasai K, Iwamoto K*. DNA methylation in schizophrenia: progress and challenges of epigenetic studies. Genome Medicine 2012,4:96.
  6. Iwamoto K*, Bundo M, Kasai K, Kato T. Measuring RNA editing of serotonin 2C receptor. Biochemistry (Moscow) 2011,76:912-914.
  7. Iwamoto K*, Bundo M, Kato T. (book chapter) RNA editing of serotonin 2C receptor and neuropsychiatric diseases. 5-HT2C receptors in the pathophysiology of CNS disease, Springer, Berlin 2010,157-167.